On 23 September 2014, my two articles on the subject of experimental folate deficiency were published in the peer-reviewed open-access journal, SpringerPlus. The articles describe two different aspects of the one experiment.; errors in red-cell folate immunoassays, and the biochemical and haematological responses to severe folate deficiency.
My self-experimentation is controversial, and publication of my articles has been very difficult, because my work challenges currently accepted dogma on:
- Reliability of pathology tests, in this case red-cell folate immunoassays
- Time taken to develop megaloblastic anaemia from folate deficiency
- Ethics of self-experimentation in medical research
The full HTML and PDF versions of both of my articles are freely available at the following SpringerPlus links:
Severe experimental folate deficiency in a human subject - a longitudinal study of biochemical and haematological responses as megaloblastic anaemia develops
http://www.springerplus.com/content/3/1/442
Severe experimental folate deficiency in a human subject - a longitudinal investigation of red-cell folate immunoassay errors as megaloblastic anaemia develops
http://www.springerplus.com/content/3/1/441
The PDF versions, and Additional files, may be downloaded from the menu on the right of the SpringerPlus HTML pages linked to above.
The primary data files, and other information, may be found on this site by following the links from the menu item PUBLISHED SCIENTIFIC RESEARCH BY THIS AUTHOR at the top of the SITE HOME PAGE. |